Galanthamine hydrobromide
NIVALIN;NIVALIN, HBR;4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-6H-BENZOFURO[3A,3,2-EF][2]BENZAZEPIN-6-OL HYDROBROMIDE;GALANTAMINE HBR;GALANTAMINE HYDROBROMIDE;GALANTHAMIDE HYDROBROMIDE;GALANTHAMINE HBR;GALANTHAMINE HYDROBROMIDE
Name: Galanthamine hydrobromide
Synonym: Nivalin
Molecular Formula:C17H21NO3.HBr;C17H22BrNO3
Molecular Weight:368.27
CAS Registry Number:1953-04-4
EINECS:217-780-5
purity: 99%
Molecular structure:
Characteristics: white crystalline powder, odorless, bitterness, soluble in water, slight soluble in ethanol, insoluble in chloroform and aether.
Ph=45.-6.5
Melting point: 258℃-264℃
Drying shrinkage: no more than 1.0%
Absorption coefficient(50μg in 1mlwater): it will be 80 at the 289nm wavelength
Function and usage:
This product is the anti-cholinesterase, weak effect. I t has strong effect to the central nervous system through the blood brain barrier. It mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc. It also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.
Clinic function: mainly used in myasthenia gravis, poliovirus quiescent stage and sequela, also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism. It’s major used in Alzheimer's disease, has the principal function for dement and dysmnesia caused by organic brain damage.
