Chelerythrine chloride
Plant source: Toddalia asiatica (L.)Lam.
Molecular formula: C21H18ClNO4
Molecular weight: 383.83
Construction:
CHELERYTHRINE(TODDALINE)(RG);1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium;1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride;Chelerythrine chloride;1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium;2,3-(Epoxymethanoxy)-5-methyl-7,8-dimethoxybenzo[c]phenanthridine-5-ium;Cheleritrine;3895-92-9 (Chloride)
CAS: 34316-15-9 3895-92-9.
Characteristics: light yellow powder or white powder, melting point: 195-205°C , 207℃(lmol ethanol) or 250℃(0.5mol water)
Specifications: 50％,90%,95%,98％ HPLC
Biological Activity:
Potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 μM) or Bad proteins and stimulates apoptosis.
Packing: 1kg/ aluminum bag
25kgs/ fiber durm or according to customer's demand
Shelf life: 2 years
